Stress Support Stack

Stress Support Stack

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Stress can have a major impact on our physical and mental health, so it's no surprise that reducing stress in our lives can lead to greater happiness and improved well-being. But what is it about stress that makes it such an important factor? Let's explore how managing stress can help improve mood, strengthen the immune system, and even increase longevity.

We wanted to do our part to make stress a little bit easier for you to manage with our Stress Support Stack.


Designed to support healthy adrenal and immune function.  An excellent boost for those with stress and fatigue.   Best taken morning and early afternoon. 

Burn Out Relief Benefits:

  • Supports adrenal function.
  • Increases energy especially afternoon fatigue.
  • Increases stress tolerance / reduces stress.
  • Helps modulate healthy inflammation levels
  • Helps normalize circadian rhythm.
  • Helps support healthy normal moods.


Licorice: Supports normal inflammation levels. Has cell protective properties. Supports adrenal functions.


Designed to support proper immune and stress responses. Excellent for stress relief, mood, and mental function enhancement. Helps to calm the nerves, increase energy and stamina, and improve focus. An excellent formula for adrenal fatigue and burnout. 

This formula contains high quality, potent adaptogenic herbs including a variety of gentle, non-stimulating ginsengs designed to increase energy, decrease stress, and help individuals heal without being overstimulating.   Contains nutrients known to support adrenal function.  

This formula is usually taken with breakfast and lunch and not taken after 4 P.M. as it can interfere with sleep in some individuals, though others have found it to help them relax in the evening. ‡

Adrenal Support helps the body to manage stress as well as play an important role in the immune system. Poorly working adrenal glands can lead to fatigue, low immunity, aches & pains, sleep issues, and many other issues. This product is a combination of potent herbs with proven adrenal gland support benefits as well as Vitamin B5. Benefits:

  • Helps strengthen the adrenal glands
  • Non stimulating adaptogenic herbals.
  • Can be used long term for chronic adrenal burnout.
  • Excellent for fatigue, low energy & poor mental function.
  • Excellent for poor stress management.

Take 1-2 capsules with breakfast and 1-2 capsules with lunch.

Caution: Make cause insomnia if taken too late in the day.


Pantothenic acid (Vitamin B5): This vitamin supports the function of the adrenal gland and the production of sex and stress hormones. It is concentrated in the adrenal glands where a lot of energy is needed to produce these hormones.

Ashwagandha root: The active ingredients in this root is important in helping the cells react normally to stressful conditions and hence cause less strain on the adrenal glands.

Rhodiola Root: Salidros is considered one of the main active ingredient in this root. Research suggests that among many other health benefits, it supports the efficacy of important antioxidant enzymes that include glutathione peroxidase. T his reduces oxidative stress on the body and so decreases stress on the adrenal gland.

Siberian and American Ginseng: Eleutherosides and ginsenosides are considered the most active compounds in these herbs. Their effects include immune support and antioxidant properties. They also support balanced inflammation in the body. Ginsenosides share the same receptor sites (agonists) with many steroidal hormones that include adrenal glucocorticoids.

Noni Fruit Extract: This extract helps in the regulation of the immune system and inflammatory processes. Other benefits include reduced stress burden on the adrenal gland and action against harmful microorganisms such as some bacteria and fungi. 

Gotu Kola Extract: Contains Triterpenes as well as other ingredients. These compounds have antioxidant and anti-inflammatory properties that support adrenal health and improve overall health and stamina.


1. Institute of Medicine. Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline. . (1998)

2. Schriner SE, et al. Protection of human cultured cells against oxidative stress by Rhodiola rosea without activation of antioxidant defenses. Free Radic Biol Med. (2009)

3. Jung SM1, Schumacher HR, Kim H, et al. Reduction of urate crystal-induced inflammation by root extracts from traditional oriental medicinal plants: elevation of prostaglandin D2 levels. Arthritis Res Ther. 2007;9(4):R64.

Ashwagandha: Supports energy production. Helps control cortisol production during stress. Supports healthy response to stress. Boosts immunity. Supports normal circadian rhythm. Supports normal utilization of oxygen, fats and proteins for more energy.

Maca: Adaptogenic and hormone balancer. Helps reduce perception of stress and anxiety. Reduces stress associated with free radicals overload in the body. Adaptogenic and hormone balancer. Reduces anxiety.

Skullcap: Has nervine properties. Helps in exhaustion and depressive states related to nervous system overload.

Panax Ginseng: Supports healthy hypothalamus-pituitary-adrenal gland axis functions. Supports normal circadian rhythm. Supports normal utilization of oxygen, fats and proteins for more energy.

Dosage: Take 1-2 capsule in the morning and again at lunch.

Contraindications: Caution with high blood pressure and/or edema due to licorice. Caution with anxiety, heart palpitations & insomnia due to panax ginseng.

Manufactured in a US FDA inspected facility.  GMP Compliant.   Purity and Potency Guaranteed!   We use the highest quality raw materials available. Testing is done at various stages of production. All IOH Nutrition Formulas Meet or Exceed cGMP Quality Standards. 

‡ These statements have not been evaluated by the FDA. These products are not intended to diagnose, treat, cure or prevent any disease.

60 Vegetarian Capsules


1. Kao, T. C., Wu, C. H., & Yen, G. C. (2014). Bioactivity and potential health benefits of licorice. Journal of agricultural and food chemistry, 62(3), 542- 553.

2. Singh, N., Bhalla, M., de Jager, P., & Gilca, M. (2011). An overview on ashwagandha: a Rasayana (rejuvenator) of Ayurveda. African journal of traditional, complementary, and alternative medicines : AJTCAM, 8(5 Suppl), 208–213. doi:10.4314/ajtcam.v8i5S.9

3. Chandrasekhar, K., Kapoor, J., & Anishetty, S. (2012). A prospective, randomized double-blind, placebo-controlled study of safety and efficacy of a high-concentration full-spectrum extract of ashwagandha root in reducing stress and anxiety in adults. Indian journal of psychological medicine, 34(3), 255–262. doi:10.4103/0253-7176.106022

4. Stansbury, J., Saunders, P., Winston, D., & Zampieron, E. R. (2012). Treating adrenal insufficiency and hypotension with glycyrrhiza. Journal of Restorative Medicine, 1(1), 102-106.

5. Agarwal, R., Diwanay, S., Patki, P., & Patwardhan, B. (1999). Studies on immunomodulatory activity of Withania somnifera (Ashwagandha) extracts in experimental immune inflammation. Journal of Ethnopharmacology, 67(1), 27-35.

6. Ley, B. M. (2003). Maca!: Adaptogen and Hormonal Regulator. Bl Publications.

7. Sandovala, M., Okuhamaa, N. N., Angelesa, F. M., Melchora, V. V., Condezob, L. A., Laob, J., & Millera, M. J. S. (2002). Antioxidant activity of the cruciferous vegetable Maca (Lepidium meyenyii). Food Chemistry, 79(207), 17.

8. Hoffmann, D. (2003). Medical herbalism: the science and practice of herbal medicine. Simon and Schuster.

9. Lee, S., & Rhee, D. K. (2017). Effects of ginseng on stress-related depression, anxiety, and the hypothalamic-pituitary-adrenal axis. Journal of ginseng research, 41(4), 589–594. doi:10.1016/j.jgr.2017.01.010 10. Liao, L. Y., He, Y. F., Li, L., Meng, H., Dong, Y. M., Yi, F., & Xiao, P. G. (2018). A preliminary review of studies on adaptogens: comparison of their bioactivity in TCM with that of ginseng-like herbs used worldwide. Chinese medicine, 13, 57. doi:10.1186/s13020-018-0214-9 


An innovative nutritional powdered product. It contains ingredients that support hormonal balance, healthy glucose metabolism, the body’s natural synthesis of catecholamines, and the inhibitory neurotransmitter GABA. This formula aims to promote a calm and relaxed emotional and physiological state.‡


  • Supports Neurotransmitter Balance
  • Supports a Relaxed & Healthy Mood.
  • Supports Focused Concentration.
  • Supports Normal Blood Pressure Levels.
  • Relax & Focus is an innovative powdered drink mix that promotes a calm, relaxed, well-balanced emotional and physiological state.*


Inositol: Present as the distinct isomer myo-inositol, inositol is a six - carbon cyclic polyalcohol occurring naturally in all living cells. The following contains some inositol, beans, grains, bean, fruits and nuts. Also, pieces of studies have shown that a 1800-2500–calorie daily diet provide only 225-1500 mg of myo-inositol, against the about 100% of ingested myo- inositol absorbed in the gastrointestinal tract, where half becomes lipid bound. In contrast to low plasma concentration, the peripheral nerves have an extraordinarily high concentration of myo-inositol. Inositol is a precursor for the second-messenger phosphatidyl-inositol system, which influence mood status differently than precursors for neurotransmitters. Based upon validated scoring procedures, double-blind, controlled, random-order crossover clinical trials using up to 18 g of myo-inositol per day for a month have demonstrated effectiveness with minimal to no side effects.

Taurine (2-aminoethanesulfonic acid): Taurine is found mainly in the intracellular space of tissues in free form . This conditionally vital amino acid maintains and coordinate cell volume via osmoregulation, a process that regulate and balance excessive or insufficient concentrations of electrolytes. In addition to its antioxidant balancing functions, taurine is important to neurotransmission, cardiac function and neuroregulation.] Taurine supplementation also increases GABA. Considered neuroprotective, taurine modulates the ability of mitochondria to buffer intracellular calcium when neurons are over stimulated and damaged. Thus, preventing cell death.

L-Theanine (N-ethyl-L-glutamine): L-Theanine is a naturally- occurring, biologically active, free-form amino acid, L-theanine known for its relaxation support, L-theanine may also support nerve health and cognition lowering glutamate levels by preventing transport of glutamate’s precursor, glutamine. It may also inhibit neurotransmission, cause inhibitory neurotransmission via glycine receptors, and thereby reduce neuronal overstimulation. L-theanine’s ability to relax the mind without inducing drowsiness has been documented by an increase in alpha wave activity during EEG recording.

Magnesium Popularly referred to as the relaxation mineral, magnesium assists in the transmission of nerve impulses and is essential to over 280 enzymatic reactions in the body. Magnesium supplementation supports a healthy mood, including during the menstrual cycle when mood changes is experienced.. In this formula we use a special ultra high absorption magnesium that have 5 times the bio availability compared to magnesium oxide.

GABA (gamma-aminobutyric acid): This neurotransmitter is an amino acid manufactured in brain cells from glutamate. Abundant in the cerebral cortex, increases the production of alpha waves directly related to a relaxed and focused stat while decreasing beta waves which is directly related to nervousness, and hyperactivity. Accurate and sufficient GABA results in the smooth, calming, regular rhythmic flow of electrical impulses in the brain is needed for emotional well-being.

‡ These statements have not been evaluated by the FDA. These products are not intended to diagnose, treat, cure or prevent any disease.

Manufactured in a US FDA inspected facility. GMP Compliant. Purity and Potency Guaranteed!   We use the highest quality raw materials available. Testing is done at various stages of production. All IOH Nutrition Formulas Meet or Exceed cGMP Quality Standards. 

CALM & FOCUS POWDER Dosage: Dissolve1 rounded scoop in a liquid of your choice 1-6 times a day.

215 Grams


1. Clements,RS,Darnell B. Myo-inositol content of common foods:development of a highmyo-inositoldiet.AmJClinNut.1980 Sep;33 (9):1954-67.http://www. 24,2011.

2. LevineJ,BarakY,GonzalvesM.Double-blind,controlledtrialofinositol treatment of depression.Am J Psychiatry.1995 May;152 (5):792-4.[PMID: 7726322]

3. PalatnikA,FrolovK,Fux M, et al.Double-blind, controlled, crossover trial ofinositolversusfluvoxamineforthetreatmentofpanic disorder.JClin Psychopharmacol.2001Jun;21(3):335-9.[PMID:11386498]

4. Fux M, Levine J,AvivA, et al.Inositoltreatment of obsessive-compulsive disorder. Am J Psychiatry. 1996 Sep;153(9):1219-21.[PMID: 8780431]

5. AbdouAM,HigashiguchiS,HorieK,etal.Relaxationandimmunity enhancement effects of gamma-aminobutyric acid (GABA) administration in humans.Biofactors.2006;26(3):201-8.[PMID:16971751].

6. FujitaT,AndoK,NodaH, et al.Effects of increased adrenomedullary activity and taurine in young patient with borderline hypertension. Circulation. 1987 Mar;75(3):525-32. [PMID:3815764]

7. L’AmoreauxWJ,MarsilloA,ElIdrissiA, et al.Pharmacological characterization ofGABAreceptorsintaurine-fedmice.JBiomedSci.2010 Aug24;17Suppl 1:S14. [PMID:20804588]

8. Kakuda T,Hinoi E,AbeA, et al.Theanine, an ingredient of green tea, inhibits [3H] glutaminetransportinneuronsandastrogliainratbrain. JNeurosciRes.2008 Jun;86(8):1846-56. [PMID:18293419]

9. YamadaT,TershimaT,OkuboT,et al.Effects oftheanine, r-glutamylethylamide, on neurotransmitter release and its relationship with glutamic acid neurotransmission.Nutr Neurosci. 2005 Aug;(8)4:219-26.[PMID: 16493792]

10. NobreAC,RaoA,Owen GN. L-theanine, a natural constituent in tea, and its effectonmental state.AsiaPac JClinNutr.2008;17Suppl 1:167-8.[PMID: 18296328]

11. Facchinetti F,Borella P,SancesG, et al.Oral magnesium successfully relieves premenstrual moodchanges.ObstetGynecol.1991Aug;78 (2):177-81.[PMID: 2067759]

12. D’Anna R,DiBenedettoV,Rizzo P,et al.Myo-inositol mayprevent gestational diabetes inPCOSwomen.GynecolEndocrinol.2012Jun;28 (6):440-2.[PMID: 22122627]

13. UnferV,CarlomagnoG,DanteG,etal.Effectsofmyo-inositolinwomenwith PCOS: a systematic reviewof randomizedcontrolledtrials. GynecolEndocrinol. 2012 Feb 1.[Epub ahead of print] [PMID: 22296306]

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