Sleep is essential for proper injury recovery due to the increased blood flow, hormones, and inflammation regulation it brings. When we enter deeper stages of sleep, our muscles receive an influx of oxygen and nutrients that help them recover and regenerate cells.

Additionally, the pituitary gland releases growth hormones that stimulate muscle repair and growth during non-REM sleep. Without adequate rest, secretion of this hormone decreases making it harder for the body to heal from injuries.

Moreover, prolactin is released while sleeping which helps regulate inflammation; when not enough sleep is obtained, inflammation in the body can become more frequent thus making it harder to recover from injuries as well as putting one at risk of further injury.

IOH CALM & FOCUS POWDER

An innovative nutritional powdered product. It contains ingredients that support hormonal balance, healthy glucose metabolism, the body’s natural synthesis of catecholamines, and the inhibitory neurotransmitter GABA. This formula aims to promote a calm and relaxed emotional and physiological state.‡

Benefits:

• Supports Neurotransmitter Balance
• Supports a Relaxed & Healthy Mood.
• Supports Focused Concentration.
• Supports Normal Blood Pressure Levels.
• Relax & Focus is an innovative powdered drink mix that promotes a calm, relaxed, well-balanced emotional and physiological state.*

Ingredients:

Inositol: Present as the distinct isomer myo-inositol, inositol is a six - carbon cyclic polyalcohol occurring naturally in all living cells. The following contains some inositol, beans, grains, bean, fruits and nuts. Also, pieces of studies have shown that a 1800-2500–calorie daily diet provide only 225-1500 mg of myo-inositol, against the about 100% of ingested myo- inositol absorbed in the gastrointestinal tract, where half becomes lipid bound. In contrast to low plasma concentration, the peripheral nerves have an extraordinarily high concentration of myo-inositol. Inositol is a precursor for the second-messenger phosphatidyl-inositol system, which influence mood status differently than precursors for neurotransmitters. Based upon validated scoring procedures, double-blind, controlled, random-order crossover clinical trials using up to 18 g of myo-inositol per day for a month have demonstrated effectiveness with minimal to no side effects.

Taurine (2-aminoethanesulfonic acid): Taurine is found mainly in the intracellular space of tissues in free form . This conditionally vital amino acid maintains and coordinate cell volume via osmoregulation, a process that regulate and balance excessive or insufficient concentrations of electrolytes. In addition to its antioxidant balancing functions, taurine is important to neurotransmission, cardiac function and neuroregulation.] Taurine supplementation also increases GABA. Considered neuroprotective, taurine modulates the ability of mitochondria to buffer intracellular calcium when neurons are over stimulated and damaged. Thus, preventing cell death.

L-Theanine (N-ethyl-L-glutamine): L-Theanine is a naturally- occurring, biologically active, free-form amino acid, L-theanine known for its relaxation support, L-theanine may also support nerve health and cognition lowering glutamate levels by preventing transport of glutamate’s precursor, glutamine. It may also inhibit neurotransmission, cause inhibitory neurotransmission via glycine receptors, and thereby reduce neuronal overstimulation. L-theanine’s ability to relax the mind without inducing drowsiness has been documented by an increase in alpha wave activity during EEG recording.

Magnesium Popularly referred to as the relaxation mineral, magnesium assists in the transmission of nerve impulses and is essential to over 280 enzymatic reactions in the body. Magnesium supplementation supports a healthy mood, including during the menstrual cycle when mood changes is experienced.. In this formula we use a special ultra high absorption magnesium that have 5 times the bio availability compared to magnesium oxide.

GABA (gamma-aminobutyric acid): This neurotransmitter is an amino acid manufactured in brain cells from glutamate. Abundant in the cerebral cortex, increases the production of alpha waves directly related to a relaxed and focused stat while decreasing beta waves which is directly related to nervousness, and hyperactivity. Accurate and sufficient GABA results in the smooth, calming, regular rhythmic flow of electrical impulses in the brain is needed for emotional well-being.

‡ These statements have not been evaluated by the FDA. These products are not intended to diagnose, treat, cure or prevent any disease.

Manufactured in a US FDA inspected facility. GMP Compliant. Purity and Potency Guaranteed!   We use the highest quality raw materials available. Testing is done at various stages of production. All IOH Nutrition Formulas Meet or Exceed cGMP Quality Standards. 

CALM & FOCUS POWDER Dosage: Dissolve1 rounded scoop in a liquid of your choice 1-6 times a day.

215 Grams

References:

1. Clements,RS,Darnell B. Myo-inositol content of common foods:development of a highmyo-inositoldiet.AmJClinNut.1980 Sep;33 (9):1954-67.http://www. ajcn.org/content/33/9/1954.AccessedOctober 24,2011.

2. LevineJ,BarakY,GonzalvesM.Double-blind,controlledtrialofinositol treatment of depression.Am J Psychiatry.1995 May;152 (5):792-4.[PMID: 7726322]

3. PalatnikA,FrolovK,Fux M, et al.Double-blind, controlled, crossover trial ofinositolversusfluvoxamineforthetreatmentofpanic disorder.JClin Psychopharmacol.2001Jun;21(3):335-9.[PMID:11386498]

4. Fux M, Levine J,AvivA, et al.Inositoltreatment of obsessive-compulsive disorder. Am J Psychiatry. 1996 Sep;153(9):1219-21.[PMID: 8780431]

5. AbdouAM,HigashiguchiS,HorieK,etal.Relaxationandimmunity enhancement effects of gamma-aminobutyric acid (GABA) administration in humans.Biofactors.2006;26(3):201-8.[PMID:16971751].

6. FujitaT,AndoK,NodaH, et al.Effects of increased adrenomedullary activity and taurine in young patient with borderline hypertension. Circulation. 1987 Mar;75(3):525-32. [PMID:3815764]

7. L’AmoreauxWJ,MarsilloA,ElIdrissiA, et al.Pharmacological characterization ofGABAreceptorsintaurine-fedmice.JBiomedSci.2010 Aug24;17Suppl 1:S14. [PMID:20804588]

8. Kakuda T,Hinoi E,AbeA, et al.Theanine, an ingredient of green tea, inhibits [3H] glutaminetransportinneuronsandastrogliainratbrain. JNeurosciRes.2008 Jun;86(8):1846-56. [PMID:18293419]

9. YamadaT,TershimaT,OkuboT,et al.Effects oftheanine, r-glutamylethylamide, on neurotransmitter release and its relationship with glutamic acid neurotransmission.Nutr Neurosci. 2005 Aug;(8)4:219-26.[PMID: 16493792]

10. NobreAC,RaoA,Owen GN. L-theanine, a natural constituent in tea, and its effectonmental state.AsiaPac JClinNutr.2008;17Suppl 1:167-8.[PMID: 18296328]

11. Facchinetti F,Borella P,SancesG, et al.Oral magnesium successfully relieves premenstrual moodchanges.ObstetGynecol.1991Aug;78 (2):177-81.[PMID: 2067759]

12. D’Anna R,DiBenedettoV,Rizzo P,et al.Myo-inositol mayprevent gestational diabetes inPCOSwomen.GynecolEndocrinol.2012Jun;28 (6):440-2.[PMID: 22122627]

13. UnferV,CarlomagnoG,DanteG,etal.Effectsofmyo-inositolinwomenwith PCOS: a systematic reviewof randomizedcontrolledtrials. GynecolEndocrinol. 2012 Feb 1.[Epub ahead of print] [PMID: 22296306]

 IOH 5X CHELATED MINERALS

This patented ULTRA-high-absorption formula is as much as five times more bioavailable than any other formula.  This formula boasts a 4:1 magnesium to calcium ratio as well as meaningful amounts of other minerals.  This formula contains the highest absorbed form of minerals available and is identical to the type of chelated minerals found in plants.  This fully-reacted, chelated mineral formula is superior to other forms. ‡

Benefits:

• Our Minerals feature unique patented ingredients sourced from Albion Labs. Albion is the world leader in innovative research and formulation of nutritional mineral products. The bioavailability of our Ultra-High Absorption 5X Chelated Minerals is up to five (5) times more than other mineral supplements in the market. This is made possible by the type of chelates we use. In addition to that, our formula is in the perfect ratio that promotes increased body stress tolerance, supports the immune system and facilitates faster and efficient toxins elimination.
• Our mineral chelates are fully reacted. This means that the chelate size, its shape and overall weight promotes better absorption, bioavailability and lower toxicity than when regular chelates are used. This supports the body with more energy at the cellular level and manages stress more effectively. These outcomes have a positive effect on the immunity. Enhanced mineral bioavailability also helps the body to improve metabolism and neurological functions.
• Independent research findings have proved that the majority of the population do not get adequate minerals from their diet. Stress and lifestyle choices have also contributed to this situation.
• Our Minerals are not combined with vitamins. This makes it easier to take your supplements while on antibiotics by taking the minerals at lunch (away from antibiotics) as many antibiotics interact with minerals therefore impairing the efficacy of the antibiotic. Another reason for separating minerals from vitamins is that while vitamins are stimulating, minerals are calming. We avoid this conflict by separating the two (Vitamins in the morning or lunch and minerals at dinner).
• This formula is formulated with the best ratio of minerals. Most mineral formulas are heavily calcium based, but research shows that too much calcium can cause many problems. This formula is more balanced with dominant magnesium as well as meaningful amounts of chromium and zinc.

*These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.

Manufactured in a US FDA inspected facility.  GMP Compliant.   Purity and Potency Guaranteed!   We use the highest quality raw materials available. Testing is done at various stages of production. All IOH Nutrition Formulas Meet or Exceed cGMP Quality Standards.

Dosage: Take 1/2 tbsp prior to bed

References:

1. Bagchi D, Stohs SJ, Downs BW, Bagchi M, Preuss HG. Cytotoxicity and oxidative mechanisms of different forms of chromium. Toxicology. 2002 Oct 30;180(1):5-22.

2. Seal, C., “Influence of dietary picolinic acid on mineral metabolism in the rat,” Ann. Nutr.

3. Metab. 32:186, 1988fully

4. McCullough ML, Robertson AS, Rodriguez C, et al. Calcium, vitamin D, dairy products, and risk of colorectal cancer in the Cancer Prevention Study II Nutrition Cohort (United States). Cancer Causes Control 2003; 14(1):1–12

5. Milner JA, McDonald SS, Anderson DE, Greenwald P. Molecular targets for nutrients involved with cancer prevention. Nutrition and Cancer 2001; 41(1–2):1–16.

6. amprecht SA, Lipkin M. Cellular mechanisms of calcium and vitamin D in the inhibition of colorectal carcinogenesis. Annals of the New York Academy of Sciences 2001; 952:73–87.

7. Sánchez M, de la Sierra A, Coca A, Poch E, Giner V, Urbano-Márquez A. Oral calcium supplementation reduces intraplatelet free calcium concentration and insulin resistance in essential hypertensive patients. Hypertension. 1997

8. Jan;29(1 Pt 2):531-6. PubMed PMID: 9039155.

9. Guerrero-Romero F, Rodriguez-Moran M. Low serum magnesium levels and metabolic syndrome. Acta Diabetol. 2002; 39: 209–213.

10. Hawkes WC, Kelley DS, Taylor PC. The effects of dietary selenium on the immune system in healthy men. Biol Trace Elem Res. 2001;81:189–213.

11. Odabasi E, Turan M, Aydin A, Akay C, Kutlu M. Magnesium, zinc, copper, manganese, and selenium levels in postmenopausal women with osteoporosis. Can magnesium play a key role in osteoporosis? Ann Acad Med Singapore. 2008 Jul;37(7):564-7.

IOH 3mg MELATONIN

Melatonin can help with difficulty falling asleep and/or staying asleep.  It can also be taken to prevent jet lag.  Our melatonin is special because it comes as a lozenge. We have found that lozenges tend to get absorbed faster for those that are in a hurry to get to sleep.‡

Manufactured in a US FDA inspected facility.  GMP Compliant.   Purity and Potency Guaranteed!   We use the highest quality raw materials available. Testing is done at various stages of production.

‡ These statements have not been evaluated by the FDA. These products are not intended to diagnose, treat, cure or prevent any disease.