GlucoLipid - Blood Sugar and Lipid Support

GlucoLipid - Blood Sugar and Lipid Support

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Cardiovascular & Metabolic Support

GlucoLipid

Bergamot phytosome, guggul, and policosanol — one capsule, and a straight answer about what that covers.

Three plant compounds that have each been studied for their role in how the body handles fats and sugars, delivered in a phytosome form built for absorption. Here is what is in it, where each ingredient has been researched, and how to take it.

502 mgBlend per capsule
1 capsulePer serving
60 capsVegetarian
VazGuard™Phytosome delivery
Why we built this one

Most people get a number before they get a plan.


You get labs back. Something is flagged. You are told to watch your diet and come back in six months. That is the whole plan. In 33 years of practice I have watched thousands of people leave that appointment with a printout and no next step, and I have watched what they do next: they buy something online, hope, and retest.

We built GlucoLipid for the person who is already doing the work — training, eating like an adult, sleeping — and wants a botanical layer on top of that work. Not instead of it. The food, the training, the sleep, the body composition, and anything your physician has prescribed are the levers that move the needle. A capsule is a small assist alongside those levers, and any brand that tells you different is selling you something.

What we can do is be specific about what is in the bottle, clear about the research behind each ingredient, and straight with you about the form and the delivery. That is the entire pitch.

Straight talk: the proprietary blend

This label declares a 502 mg proprietary blend. That means the individual amounts of bergamot, guggul, and policosanol are not broken out — you get the total, not the split. We would rather tell you that in the first screen than let you find it on the panel.

Why it matters: most of the human research on bergamot polyphenols has used several hundred milligrams to more than a gram per day of the polyphenol fraction on its own. The entire blend here is 502 mg per capsule before it is divided three ways. Phytosome delivery is designed to make a smaller amount of plant compound go further, which is exactly why we chose that form — but we are not going to hand you a study number and let you assume this capsule reproduces it.

Read this page as what it is: a well-formed, well-sourced botanical blend in an absorption-forward delivery, positioned as support alongside the things that actually move your labs. Not as a stand-in for them.

The difference

Same three botanicals. Not the same formula.

The typical shelf version

  • Bergamot listed as a generic fruit extract, no form, no supplier, no delivery system
  • Guggul as unstandardized gum resin, so the active fraction varies lot to lot
  • Policosanol with no octacosanol percentage on the label
  • Soy lecithin as the phospholipid carrier
  • Big cholesterol numbers pulled from studies the product itself never ran
  • Delivery, standardization and supplier all left to the customer to guess at

The IOH standard

  • Bergamot as VazGuard™ phytosome from Indena S.p.A., named on the label, not hidden behind "proprietary extract"
  • Guggul standardized to a 2.5% extract, declared on the panel
  • Policosanol standardized to 30% octacosanol, declared on the panel
  • Sunflower lecithin as the phospholipid carrier
  • No borrowed research percentages. If a study used a different dose or form, we say so or we leave the number out
  • The research base for each of the three botanicals laid out on the page, not buried
What it supports

Four jobs, stated plainly.

01

Healthy lipid metabolism

Supports the body's normal handling of cholesterol and triglycerides in people whose levels are already within a healthy range.

02

Healthy glucose metabolism

Supports normal glucose metabolism and the cellular signaling involved in how tissue takes up and uses fuel.

03

Cardiovascular and liver support

Citrus polyphenols support cardiovascular health and normal liver function as part of a broader nutrition and training program.

04

Absorption-forward delivery

Phytosome technology binds the citrus polyphenols to phospholipids, a form designed to improve how well plant compounds are taken up.

The research file

Where each ingredient has been studied.


Three botanicals, three separate bodies of research. Here is what has actually been looked at for each one, and the form we chose to deliver it in.

Ingredient
What the research has looked at
Research base
Bergamot polyphenolsVazGuard™ phytosome
The most researched of the three. Controlled human trials, largely from Italian research groups, have examined bergamot polyphenol fractions and markers of lipid and glucose metabolism. Those trials used a standalone polyphenol fraction; we chose the phytosome form here because binding polyphenols to phospholipids is specifically engineered to improve how much of the compound the body takes up.
Human clinical trials
GuggulCommiphora mukul, 2.5% extract
More than two thousand years of documented Ayurvedic use for lipid and metabolic support, and a modern research literature built around the guggulsterones — the ketonic steroid compounds that interact with the nuclear receptor signaling governing bile acid production. Standardizing to a 2.5% extract is what keeps that active fraction consistent from lot to lot instead of leaving it to the raw resin.
Traditional use plus clinical study
Policosanol30% octacosanol
Studied in randomized, placebo-controlled human trials across several countries, including Cuba, Japan and Korea, for lipid metabolism, vascular function and blood pressure already in the normal range. Results in that literature track closely with the quality and composition of the source material, which is exactly why ours is standardized to 30% octacosanol rather than sold as unspecified plant wax.
Randomized human trials

Three different mechanisms, three different points in the same system: how the liver makes cholesterol, how bile clears it, and how the vessels and cells handle what is circulating. That is the reason these three are in one capsule instead of three bottles.

Inside the formula

Three actives. One capsule.


All three sit inside a single 502 mg proprietary blend, so the individual milligram amounts are not disclosed on the label. Where we describe what each one does, we are describing the ingredient, not making a promise about what this specific amount will do in you.

Bergamot Orange

Within 502 mg blend

Citrus bergamia Risso et Poiteau (fruit) · VazGuard™ phytosome with sunflower lecithin

Bergamot is a citrus fruit grown almost exclusively along the Calabrian coast of southern Italy. What makes it interesting is not vitamin C — it is an unusual group of flavanones, including brutieridin and melitidin, that are not found at meaningful levels in other citrus. Research interest in these compounds centers on the HMG-CoA reductase step, the point in the liver where the body manufactures its own cholesterol, and on AMPK signaling, the cellular sensor that governs how tissue decides to store or burn fuel.

The form matters as much as the plant. Polyphenols are notoriously poorly absorbed on their own. A phytosome binds the plant compound to phospholipids so it presents to the gut wall in a form the body handles more readily. VazGuard™ is Indena's bergamot phytosome, made in Italy, and it is named on our label because we think you should know exactly whose material you are buying.

Supports healthy cholesterol and triglyceride levels already within the normal range, and supports healthy glucose metabolism.

Guggul

Within 502 mg blend

Commiphora mukul (gum resin) · 2.5% extract

Guggul is the resin of the mukul myrrh tree, used in Ayurvedic practice for lipid and metabolic support for well over two thousand years. The compounds of interest are the guggulsterones, which interact with the nuclear receptor signaling that governs bile acid production — and bile acid production is one of the main routes the body uses to clear cholesterol. Standardizing to a 2.5% extract means the active fraction is controlled lot to lot rather than left to whatever the raw resin happened to contain.

Supports healthy lipid metabolism and normal bile production.

Policosanol

Within 502 mg blend

30% octacosanol · long-chain plant fatty alcohols

Policosanol is a mixture of long-chain fatty alcohols isolated from plant wax, with octacosanol as the primary component. It has been studied for its role in lipid metabolism and vascular function, and it is standardized here to 30% octacosanol so you know what fraction of the material is the compound of interest rather than accompanying waxes.

Supports healthy lipid metabolism and normal blood vessel function.

Supplement Facts

Exactly what the label says.

Supplement Facts

Serving Size: 1 Capsule

Amount Per Serving   % DV
Proprietary Blend: 502 mg *
Bergamot Orange (fruit) (Citrus bergamia Risso & Poit.) (as Bergamot Phytosome Extract and Sunflower Lecithin) (VazGuard™)  
Guggul (gum) (Commiphora mukul) (2.5% Extract) *
Policosanol (30% Octacosanol) *

* Daily Value (DV) not established.

Other Ingredients: Vegetarian capsule (hypromellose, purified water), sunflower lecithin, rice flour.

VazGuard™ is a trademark of Indena S.p.A., Italy.

Transcribed from the printed label, which is also shown in the product images. Contains no soy, no gluten ingredients, no artificial colors or flavors. 60 vegetarian capsules per bottle.

What it is

A three-botanical capsule built around bergamot polyphenols in a phytosome delivery form, with standardized guggul and policosanol alongside. 60 vegetarian capsules.

What it does

Supports healthy cholesterol and triglyceride levels already within the normal range, supports healthy glucose metabolism, and supports cardiovascular and liver health.

Who it's for

Adults who want botanical support for lipid and glucose metabolism alongside their nutrition, training, and whatever their physician has them on. Not a substitute for any of it.

How to take it

The label allows 1 to 2 capsules, one to two times daily, with food. Most people will do well starting at 1 capsule twice daily with meals. At that rate a bottle is a 30-day supply.

Honest expectations

What the first 90 days actually look like.


Nobody feels their lipid panel. This is not a pre-workout — there is no cue that it is working, and any brand that promises you one by a certain week is guessing. Here is the realistic version.

Weeks 1–2

Nothing to feel, and that is normal

Take it with food and build the habit. Some people notice mild digestive adjustment in the first few days with any botanical resin; taking it with a real meal usually settles it. If it does not settle, stop and talk to your physician.

Weeks 3–10

The part that actually matters

This is where the rest of the program does the heavy lifting. Fiber, protein, resistance training, sleep, alcohol, and body composition move metabolic markers far more than any capsule. GlucoLipid is riding along with that work, not replacing it.

Around day 90

Retest, do not guess

Get a lab panel through your physician and compare it to your baseline. That is the only honest scoreboard here. If nothing moved, that is worth knowing too, and we would rather you find out than keep buying on faith.

What to look for

How to read any bergamot formula, including ours.


We are not naming competitors. Take this list to any product in the category, ours included, and see how it holds up.

What to check Typical off-the-shelf version GlucoLipid
Bergamot delivery form Plain fruit extract or powder, delivery form unstated Phytosome, bound to phospholipids for uptake
Ingredient supplier named "Proprietary bergamot extract," no owner disclosed VazGuard™ from Indena S.p.A., Italy, printed on the label
Guggul standardization Raw gum resin, active fraction unstated 2.5% extract, declared on the panel
Policosanol standardization "Policosanol" with no octacosanol percentage 30% octacosanol, declared on the panel
Phospholipid source Soy lecithin Sunflower lecithin
Capsule Bovine or porcine gelatin Vegetarian hypromellose
Research transparency Study percentages quoted with no mention of the dose or form the study used The research base for each ingredient stated on the page, no borrowed numbers
Proof, not promises

What we will stand behind.

  • Named, trademarked bergamot material from a disclosed supplier
  • Two of three actives standardized to a declared percentage
  • Blend total printed on the label, and discussed openly on this page
  • Sunflower lecithin, not soy
  • Vegetarian capsule, rice flour, nothing else
  • No proven, no guaranteed, no borrowed study percentages
  • Manufactured in an FDA-registered, cGMP-compliant facility
IOH Nutrition GlucoLipid, Blood Sugar and Lipid Support, 60 vegetarian capsules
Quality and manufacturing

Where this is made, and what we do and don't claim.


Facility

Manufactured in the United States in an FDA-registered, cGMP-compliant facility. FDA registers facilities; it does not approve them, and we will not word it any other way.

Raw materials

Branded bergamot phytosome from Indena S.p.A. in Italy. Guggul and policosanol supplied as standardized extracts to a declared active percentage.

Testing

Testing is performed at stages of production, and our formulas are made to meet or exceed cGMP standards. We do not publish a lot-specific certificate of analysis for this product, so we do not claim one.

Dr. Andreas Boettcher at an Ironman finish line with his son

Dr. Andreas Boettcher · Ironman finish. Not a product claim.

I am 56, medication-free, and I still race. That is not a promise I can make to you, and it is not something a capsule did. It came from three decades of training, eating, sleeping, and getting my own labs pulled and looked at. What a formula like this can do is sit on top of that work. I would rather sell you fewer bottles and tell you the truth about where the evidence is thin.

Dr. Andreas Boettcher, B.S., D.C., C.F.M.P.

Founder, It's Only Halftime

  • Ironman Triathlete
  • Master's Men's Physique Competitor
  • Medication-Free at 56
  • 33 Years of Clinical Practice
Stacks

What we run alongside it.


One product, one job. When someone is working on lipid and glucose markers together, this is the pairing we reach for.

IOH Nutrition Berberine Complex, Ultra High Potency Intestinal and Gut Support

GlucoLipid + Berberine

Berberine — Ultra High Potency Intestinal and Gut Support · Three-root 4:1 complex · 90 capsules

Bergamot polyphenols and berberine are both studied for their activity at AMPK, the nutrient-sensing enzyme that governs whether a cell stores fuel or burns it. They arrive at it from opposite ends of the system. Berberine barely absorbs, which turns out to be the point: the overwhelming majority of it stays in the intestinal lumen, where the research on microbial composition, bile acid handling, and intestinal nutrient signaling is concentrated. The bergamot flavanones work systemically, further upstream, at the liver step where the body manufactures its own cholesterol.

Gut end and liver end of the same metabolic conversation. That is why we run them together rather than asking you to choose one. Take GlucoLipid with a meal and Berberine Complex with a meal, on whatever schedule your directions and your physician support.

One caution worth naming: the goldenseal in Berberine Complex inhibits the CYP3A4 enzyme system, and bergamot is a citrus carrying furanocoumarins that touch the same pathway. If you take prescription medication, run this pairing past your pharmacist before you stack them, not after.

See IOH Berberine

Know what you are buying, know what the research behind it looks like, and get a lab panel at 90 days so you are working from numbers instead of hope.

Stay Strong,

Dr. Andreas

Dr. Andreas Boettcher, B.S., D.C., C.F.M.P.

Questions, answered

The ones worth asking.

Can I take this instead of my prescription?

No. GlucoLipid is a dietary supplement. It is not a substitute for any medication, and nothing on this page should be read as a reason to stop, reduce, or delay anything your physician has prescribed. Do not change a prescription without your prescriber. If your goal is to get to a place where your physician is willing to revisit your medications, that conversation belongs with them, with lab work behind it.

Medication interactions: read this one before you order.

This formula has real interaction potential. Talk to your physician or pharmacist before starting if you take anything in these classes:

  • Statins and other lipid-lowering medications. Bergamot is a citrus fruit that contains furanocoumarins, the same family of compounds that make grapefruit a concern with certain medications processed by the CYP3A4 enzyme.
  • Calcium channel blockers and beta blockers. Guggul has been reported to affect blood levels of certain medications in these classes, including diltiazem and propranolol.
  • Thyroid medication. Guggul has been reported to influence thyroid-related measures. If you are on thyroid replacement, your physician should know.
  • Anticoagulants and antiplatelet medications. Both guggul and policosanol have been discussed in the literature in relation to platelet function.
  • Medications that lower blood sugar. If you monitor glucose, keep monitoring and tell your prescriber you have added this.
  • Anything else metabolized through the liver. When in doubt, ask your pharmacist and bring the label.

Not for use during pregnancy or while nursing. Guggul in particular is not recommended in pregnancy.

Why doesn't the label show how much of each ingredient is in there?

Because it is declared as a proprietary blend, which discloses the 502 mg total but not the split between bergamot, guggul, and policosanol. We think you deserve the breakdown, and we say so plainly rather than hoping you do not notice. Judge the formula on what is disclosed: the material source, the delivery form, the standardization percentages, and our own honest read on the evidence.

How many capsules should I actually take?

The label allows 1 to 2 capsules, one to two times daily, with food. That is a wide range, so here is a practical answer: start at 1 capsule twice daily with meals. At that rate, a 60-capsule bottle is 30 days. If you and your physician decide to go to the top of the label range, a bottle is 15 days. Always take it with food.

Is this soy-free and vegetarian?

Yes to both. The phospholipid carrier is sunflower lecithin, not soy, and the capsule is hypromellose rather than gelatin. Other ingredients are the vegetarian capsule, sunflower lecithin, and rice flour. Nothing else.

When will I notice something?

You will not feel this working, and we are not going to give you a timeline. Lipid and glucose markers are measured, not felt. Retest with your physician at around 90 days against a baseline drawn before you started, and let the numbers tell you.

What should I stack this with?

Berberine Complex. Both formulas sit in the AMPK conversation, but from different ends of the system — berberine stays almost entirely in the intestinal lumen, while the bergamot flavanones work systemically at the liver. Gut end and liver end, run together. See the stack section above for the full reasoning, including the CYP3A4 caution that applies if you take prescription medication.

Do I still need to change my diet and train?

Yes. That is the whole program; this is a supporting piece of it. Fiber, protein, resistance training, sleep, alcohol, and body composition drive metabolic markers in a way no capsule matches. If you are looking for the thing that lets you skip that work, it is not on this page and it is not on anyone else's either.

The close

Know exactly what you are taking, and why.

Three botanicals, one in a delivery form built for absorption, from a supplier we are willing to name. A label that discloses its standardizations. And a page that told you where the evidence is strong and where it is not, before you spent a dollar.

That is the trade we are offering: fewer promises, more information. Add GlucoLipid to the work you are already doing, get a baseline panel, and retest in 90 days.

Trademark attribution: VazGuard™ is a trademark of Indena S.p.A., Italy. All other trademarks are the property of their respective owners.

Manufacturing: Manufactured in the United States in an FDA-registered facility in compliance with current Good Manufacturing Practices. Testing is performed at stages of production. IOH Nutrition formulas are made to meet or exceed cGMP quality standards.

Use responsibly. Consult your physician before use, particularly if you are pregnant, nursing, have a medical condition, or take prescription medication, including lipid-lowering, blood pressure, thyroid, blood-thinning, or blood-sugar medications. Discontinue use and contact your physician if you experience an adverse reaction. Keep out of reach of children. Store in a cool, dry place.

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

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